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This course is designed for healthcare professionals including doctors, nurses, and pharmacists who are involved in paediatric care. It focuses on the integration of evidence-based complementary therapies with conventional medical approaches, emphasising the management of paediatric conditions such as epilepsy, neurodevelopmental and behavioural disorders, and Paediatric Acute-onset Neuropsychiatric Syndrome (PANS). Participants will explore the use of cannabinoid-based medicines alongside lifestyle, diet, and supplement strategies, gaining practical insights into the endocannabinoid system’s role in brain development and child health. The course aims to equip prescribers with up-to-date, evidence-based education to improve their confidence in managing these complex conditions.

Successful completion will be one of the requirements under the ANZCCP HREC AP paediatric approval pathway.

ANZCCP Members 20% discount: 
Find your member discount code here or email [email protected] for a discount code before purchasing.

Accredited by the RACGP

Learning Outcomes
Upon completion of the education, participants will be able to:

  • Describe the principal aspect of human brain development.
  • Identify the major roles  of the endocannabinoid system.
  • Summarise the major risks and benefits of using CBD and THC during childhood and adolescence.
  • Determine safety considerations in prescribing and titrating cannabinoid-based medications.
  • Summarise best practice recommendations in medication selection, dosing, and titration for cannabinoid-based treatments. 
  • Identify current Australian TGA guidelines for the use of cannabinoid-based medicines for the management of paediatric epilepsy.
  • Compare different nutritional intervention for epilepsy.
  • Evaluate and communicate best practices for the daily administration of medicinal cannabis to patients.
  • Describe the symptoms and signs of PANS and PANDAS.
  • Implement different strategies for the management of PANS/PANDAS.

Curriculum:

TopicPresenter
 Module 1: Introduction:
* Introduction to human brain development
* The Endocannabinoid System (ECS)
* Brain development and the ECS
* The ECS and Foetal Development
* Adolescent Brain Development & The ECS * Summary and implications 
Dr Orit Holtzman, MBBS, PhD (Neuroscience) 
Module 2: Brain development and Phytocannabinoids:
* Brain development and phytocannabinoids- Introduction
* THC and CBD- Pharmacology
* Brain development and Phytocannabinoids- THC
* Drug addiction and THC
* Neuropsychiatric disorders and THC
* Cognitive Function and THC
* CBD & the Developing Brain
* Drug Addiction & CBD
* Neuropsychiatric disorders and CBD
* CBD and Cognitive Function pre-clinical and clinical evidence
Dr Orit Holtzman, MBBS, PhD (Neuroscience) 
Module 3: Paediatric Epilepsy
* Epilepsy- definition
* Pathophysiology of Epilepsy
* Epileptogenesis
* Comorbidities
* The ECS and Epilepsy
* The ECS, Neuroinflammation and Epilepsy
* CBD & Epilepsy- mechanisms of action
* CBD & Neuroinflammation
* Δ9-THC and epilepsy
* Δ9-THC Mechanism of Action
* Δ9-THC & Neuroinflammation
* Other Cannabinoids
* The role of MC in Epilepsy
* Adverse events in Epilepsy
* Cannabidiol- approval by the TGA
* Beyond CBD- full spectrum MC in Paediatric Epilepsy benefits and risks
* TGA Guidelines for the Mx of Epilepsy with MC
* Drug interactions
* Summary and implications
Dr Orit Holtzman, MBBS, PhD (Neuroscience) 
Module 4: Paediatric Epilepsy case study
* Management of a young child with treatment resistant epilepsy with CBD
Dr Orit Holtzman, MBBS, PhD (Neuroscience) 
Module 5: Nutritional interventions for Epilepsy 
* Definition and evidence for the different Ketogenic diets 
* Side effects and limitations
* Dairy and Wheat – are they necessary to remove?
* Aspartame
* Nutritional deficiencies and Antiepileptic medications (AEDs) 
* Case studies
Sonya ReynoldsBA, Dip Nutrition, Grad Cert Nutrition 
Module 6: Medicinal cannabis for paediatric developmental-behavioural disorders 
* Paediatric psychopharmacology
* Principles of quality prescribing
* Non-pharmacological supports
* Medicinal Cannabis: Side-effects
* Medicinal Cannabis: Paediatric drug interactions
Medicinal cannabis for paediatric emotional and behavioural symptoms: Parent and physician perspectives
* Evidence for cannabinoids in paediatric behavioural disorders
– Fragile X
– ASD
– Anxiety
* Review of current trials
*Personal practice 
A/Prof Daryl Efron, MBBS, FRACP, MD
Module 7: PANS/PANDAS
* PANS (Paediatric Acute- onset Neuropsychiatric Syndrome) definition
*Diagnosis
* Causes
* Pathophysiology
* Treatment goals
* Pharmacological treatment
* Oral and gut microbiome in PANS/PANDAS
* Nonpharmacological management
* Immune Modulation
* Recurrences
* Diagnosis and treatment summary
Dr Leila Masson, MD, MPH, FRACP